St. Ann is a somewhat small city located in the state of Missouri. With a population of 12,755 people and five associated neighborhoods, St. Ann is the 58th largest community in Missouri.

Also of interest is that St. Ann has more people living here who work in computers and math than 95% of the places in the US.

A relatively large number of people in St. Ann telecommute to their jobs. Overall, about 7.32% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

The percentage of adults in St. Ann with college degrees is slightly lower than the national average of 21.84% for all communities. 16.07% of adults in St. Ann have a bachelor's degree or advanced degree.

The per capita income in St. Ann in 2022 was $26,790, which is middle income relative to Missouri, and lower middle income relative to the rest of the US. This equates to an annual income of $107,160 for a family of four. However, St. Ann contains both very wealthy and poor people as well.

St. Ann is an extremely ethnically-diverse city. The people who call St. Ann home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of St. Ann residents report their race to be White, followed by Black or African-American. Important ancestries of people in St. Ann include German, Irish, English, Italian, and French.

The most common language spoken in St. Ann is English. Other important languages spoken here include Spanish and African languages.