Port St. Lucie is a relatively large coastal city (i.e. on the ocean, a bay, or inlet) located in the state of Florida. With a population of 231,790 people and 40 associated neighborhoods, Port St. Lucie is the seventh largest community in Florida. There's nothing like the smell of a brand new house, and in Port St. Lucie, you'll find that a large proportion of houses were recently built. New growth in residential real estate is an indication that people are choosing to move to Port St. Lucie, and putting down their money on brand new construction. Port St. Lucie’s real estate is, on average, some of the newest in the nation. Port St. Lucie does seem to be experiencing an influx of affluent people, because the median household income is $75,040.00.

Also of interest is that Port St. Lucie has more people living here who work in computers and math than 95% of the places in the US.

Telecommuters are a relatively large percentage of the workforce: 8.96% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Port St. Lucie is also nautical, which means that parts of it are somewhat historic and touch the ocean or tidal bodies of water, such as inlets and bays. Such areas are often places that visitors and locals go for waterfront activities or taking in the scenery.

In Port St. Lucie, however, the average commute to work is quite long. On average, people spend 30.74 minutes each day getting to work, which is significantly higher than the national average.

The percentage of people in Port St. Lucie who are college-educated is somewhat higher than the average US community of 21.84%: 26.18% of adults in Port St. Lucie have at least a bachelor's degree.

The per capita income in Port St. Lucie in 2022 was $35,301, which is middle income relative to Florida, and upper middle income relative to the rest of the US. This equates to an annual income of $141,204 for a family of four. However, Port St. Lucie contains both very wealthy and poor people as well.

Port St. Lucie is an extremely ethnically-diverse city. The people who call Port St. Lucie home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Port St. Lucie residents report their race to be White, followed by Black or African-American. Port St. Lucie also has a sizeable Hispanic population (people of Hispanic origin can be of any race). People of Hispanic or Latino origin account for 22.88% of the city’s residents. Important ancestries of people in Port St. Lucie include Irish, Italian, German, English, and Haitian.

Foreign born people are also an important part of Port St. Lucie's cultural character, accounting for 19.52% of the city’s population.

The most common language spoken in Port St. Lucie is English. Other important languages spoken here include Spanish and French.